Successful low-dose leflunomide treatment for ganciclovir-resistant cytomegalovirus infection with high-level antigenemia in a kidney transplant: A case report and literature review

Shinya Morita; Kazunobu Shinoda; Satoshi Tamaki; Hidaka Kono; Hiroshi Asanuma; Ken Nakagawa; Mototsugu Oya

doi:10.1016/j.jcv.2016.07.015

Successful low-dose leflunomide treatment for ganciclovir-resistant cytomegalovirus infection with high-level antigenemia in a kidney transplant: A case report and literature review

Shinya Morita, Kazunobu Shinoda, Satoshi Tamaki, Hidaka Kono, Hiroshi Asanuma, Ken Nakagawa, Mototsugu Oya

泌尿器科学

研究成果: Article › 査読

10 被引用数 (Scopus)

抄録

Ganciclovir-resistant cytomegalovirus infection is sometimes life-threatening for organ transplant recipients. Foscarnet is an alternative, although it may potentially worsen the preexistent impaired renal function. Here we report the case of a successful low-dose leflunomide treatment in a kidney transplant recipient with very high viral replication, who underwent kidney transplantation 10 years before. Administering 10 mg leflunomide daily for 5 months without a loading dose completely cleared the ganciclovir-resistant cytomegalovirus strains.

本文言語	English
ページ（範囲）	133-138
ページ数	6
ジャーナル	Journal of Clinical Virology
巻	82
DOI	https://doi.org/10.1016/j.jcv.2016.07.015
出版ステータス	Published - 2016 9月 1

ASJC Scopus subject areas

ウイルス学
感染症

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1016/j.jcv.2016.07.015

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引用スタイル

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AU - Tamaki, Satoshi

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