Successful treatment of lupus protein-losing enteropathy with belimumab: A case report

Marenori Kojima; Hironari Hanaoka; Kaito Aoki; Hiromi Matsushita; Hiroshi Ito; Hidehiro Yamada

doi:10.1093/mrcr/rxae010

Successful treatment of lupus protein-losing enteropathy with belimumab: A case report

Marenori Kojima
, Hironari Hanaoka
, Kaito Aoki
, Hiromi Matsushita
, Hiroshi Ito
, Hidehiro Yamada

内科学(リウマチ・膠原病)

研究成果: Article › 査読

1 被引用数 (Scopus)

抄録

Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.

本文言語	English
ページ（範囲）	264-266
ページ数	3
ジャーナル	Modern Rheumatology Case Reports
巻	8
号	2
DOI	https://doi.org/10.1093/mrcr/rxae010
出版ステータス	Published - 2024 7月 1

ASJC Scopus subject areas

リウマチ学

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10.1093/mrcr/rxae010

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abstract = "Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.",

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AU - Matsushita, Hiromi

AU - Ito, Hiroshi

AU - Yamada, Hidehiro

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N2 - Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.

AB - Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.

KW - Systemic lupus erythematosus

KW - belimumab

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Successful treatment of lupus protein-losing enteropathy with belimumab: A case report

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