Sudden death of an infant with 'an early epileptic encephalopathy'

Li Quan, Bao Li Zhu, Kaori Ishida, Mari Taniguchi, Dong Ri Li, Yasunobu Kamikodai, Masaki Q. Fujita, Hitoshi Maeda

研究成果: Article査読

4 被引用数 (Scopus)

抄録

This article reports an autopsy case of sudden death of an infant with an infrequent encephalopathy involving epileptic episodes. The infant was a 1-year and 10-month-old boy, who had a history of the first convulsive seizures in the third month after birth. The clinical diagnosis was described as 'an early infantile epileptic encephalopathy with suppression-bursts' (Ohtahara syndrome). On a winter day, he was collapsed following a high fever and was already dead on the arrival at a hospital. The body was small for the age and poorly nourished. The autopsy and postmortem magnetic resonance imaging scan (MRI) of formalin-fixed brain revealed advanced unsymmetric brain atrophy with cortical dysplasia, which were prominent in the left temporal and right occipital lobes, and sclerotic atrophy of the parahippocampal gyri, additionally showing a feature of the olivo-ponto-cerebellar atrophy. However, the cause of death was pathologically and microbiologically determined as bacterial bronchopneumonia following pulmonary infection of the influenza A virus. In sudden death cases of physically handicapped infants, the investigation of viral infection in consideration of an epidemiological survey is important even when the death can be pathomorphologically explained.

本文言語English
ページ(範囲)62-67
ページ数6
ジャーナルForensic Science International
124
1
DOI
出版ステータスPublished - 2001 12月 15
外部発表はい

ASJC Scopus subject areas

  • 病理学および法医学

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