Supramolecular approaches for cellular modulation

研究成果: Chapter

4 被引用数 (Scopus)


The surface layer of the cell membrane plays important roles in interactions between the cells and their surroundings, e.g., other cells, soluble biological molecules, and extracelluar matrices (Figure 17.1). Cellular recognition is usually initiated by direct contact with biologically functional molecules at the cell surfaces. The mechanical stress stimulates cell activation in some circumstances. Specific interactions between receptors and ligands are important for cellular recognition. In many cases, multivalent binding (multivalency) can strengthen the ligand-receptor adhesion. In intercellular communication, accessory receptors are often required to stabilize the interaction by increasing the overall strength of the cell-cell adhesion, and co-receptors help activate cells by generating their own intracellular signals. Different combinations of receptors are likely to form complexes that transmit signals across membranes.

ホスト出版物のタイトルSupramolecular Design for Biological Applications
出版社CRC Press
出版ステータスPublished - 2002 1月 1

ASJC Scopus subject areas

  • 医学(全般)
  • 生化学、遺伝学、分子生物学(全般)
  • 工学(全般)
  • 材料科学(全般)


「Supramolecular approaches for cellular modulation」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。