Synthesis of (2S,5S)-bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine from D-mannitol

Tony K.M. Shing

doi:10.1016/S0040-4020(01)86097-X

Synthesis of (2S,5S)-bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine from D-mannitol

Tony K.M. Shing

研究成果: Article › 査読

41 被引用数 (Scopus)

抄録

A short, efficient, and practical synthesis of (2S,5S)-bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine from D-mannitol involving five sequential reactions (benzylidenation, trifluoromethanesulphonation, hydrazinolysis, hydrogenolysis, and deacetalisation) is described.

本文言語	English
ページ（範囲）	7261-7264
ページ数	4
ジャーナル	Tetrahedron
巻	44
号	23
DOI	https://doi.org/10.1016/S0040-4020(01)86097-X
出版ステータス	Published - 1988
外部発表	はい

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/S0040-4020(01)86097-X

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引用スタイル

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abstract = "A short, efficient, and practical synthesis of (2S,5S)-bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine from D-mannitol involving five sequential reactions (benzylidenation, trifluoromethanesulphonation, hydrazinolysis, hydrogenolysis, and deacetalisation) is described.",

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AB - A short, efficient, and practical synthesis of (2S,5S)-bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine from D-mannitol involving five sequential reactions (benzylidenation, trifluoromethanesulphonation, hydrazinolysis, hydrogenolysis, and deacetalisation) is described.

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U2 - 10.1016/S0040-4020(01)86097-X

DO - 10.1016/S0040-4020(01)86097-X

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AN - SCOPUS:0346222479

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Synthesis of (2S,5S)-bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine from D-mannitol

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