TY - JOUR
T1 - The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms
AU - Abbate, Pasquale Marco
AU - Hasibul Hasan, A. T.M.
AU - Venier, Alice
AU - Vauclin, Vincent
AU - Pizzuto, Silvia
AU - Sgreccia, Alessandro
AU - Di Maria, Federico
AU - Coskun, Oguzhan
AU - Mizutani, Katsuhiro
AU - Rodesch, Georges
AU - Consoli, Arturo
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/6/1
Y1 - 2022/6/1
N2 - A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm’s development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.
AB - A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm’s development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.
KW - arterial wall
KW - hemodynamics
KW - intracranial aneurysm
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U2 - 10.3390/app12125964
DO - 10.3390/app12125964
M3 - Review article
AN - SCOPUS:85132250138
SN - 2076-3417
VL - 12
JO - Applied Sciences (Switzerland)
JF - Applied Sciences (Switzerland)
IS - 12
M1 - 5964
ER -