(1) Background: Despite the number of complicated and expensive spine surgery proce-dures maintained by the national health insurance system in Japan, until now there has been no large‐scale multicenter clinical database for this field to understand and improve healthcare ex-penditure and treatment outcomes. The purpose of this report is to announce the establishment and methodology of a nationwide registry system for spinal instrumentation surgeries by the Japanese Spinal Instrumentation Society (JSIS), and to report the progress over the first 1.5 years of this data-base’s operation. (2) Methods: The JSIS recently produced an online database with an electronic server. The collected information included patient background, surgery information, and early complications of primary and revision cases. Analysis included data from February 2018, when regis-tration began, to August 2019. (3) Results: As of August 2019, 73 facilities have completed the re-quired paperwork to start, and 55 facilities have registered cases. Of the total 5456 registered cases, 4852 were valid and 2511 were completed. (4) Conclusions: JSIS‐DB, the nationwide web‐based registry system for spinal instrumentation surgery in Japan, was launched for the purpose of research, healthcare policy regulation, and improved patient care, and its methodology and progress in the first 1.5 years are reported in this study.
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