TY - JOUR
T1 - The first case of concomitant Mycobacterium Genavense lymphadenitis and EBV-positive lymphoproliferative disorder
AU - Ito, Yusuke
AU - Takaoka, Kensuke
AU - Toyama, Kazuhiro
AU - Taoka, Kazuki
AU - Wakabayashi, Yoshitaka
AU - Shinozaki-Ushiku, Aya
AU - Okazaki, Aiko
AU - Chikamatsu, Kinuyo
AU - Mitarai, Satoshi
AU - Ushiku, Tetsuo
AU - Kurokawa, Mineo
N1 - Publisher Copyright:
© 2020 Universita Cattolica del Sacro Cuore. All rights reserved.
PY - 2020
Y1 - 2020
N2 - This is the first case of concurrent Mycobacterium genavense lymphadenitis and Epstein-Barr virus (EBV)-positive lymphoproliferative disorder (LPD) in the same lymph node with no immunocompromised history. M. genavense infection is a rare opportunistic infection mainly for human immunodeficiency virus (HIV)-infected patients. Although no immunodeficiency was detected in our patient, our case indicates that the immunodeficiency in the background of EBV latency type III and the immunosuppression by malignant lymphoma itself might induce the M. genavense lymphadenitis. This case highly alerts clinicians to the immunosuppressive state of EBV-positive LPD with latency type III even if any immunodeficient serological factors are not detected.
AB - This is the first case of concurrent Mycobacterium genavense lymphadenitis and Epstein-Barr virus (EBV)-positive lymphoproliferative disorder (LPD) in the same lymph node with no immunocompromised history. M. genavense infection is a rare opportunistic infection mainly for human immunodeficiency virus (HIV)-infected patients. Although no immunodeficiency was detected in our patient, our case indicates that the immunodeficiency in the background of EBV latency type III and the immunosuppression by malignant lymphoma itself might induce the M. genavense lymphadenitis. This case highly alerts clinicians to the immunosuppressive state of EBV-positive LPD with latency type III even if any immunodeficient serological factors are not detected.
KW - Epstein-Barr virus-positive lymphoproliferative disorder (EBV-LPD)
KW - Mycobacterium genavense
KW - Programmed cell death 1 ligand 1 (PD-L1)
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U2 - 10.4084/MJHID.2020.035
DO - 10.4084/MJHID.2020.035
M3 - Article
AN - SCOPUS:85089120089
SN - 2035-3006
VL - 12
JO - Mediterranean Journal of Hematology and Infectious Diseases
JF - Mediterranean Journal of Hematology and Infectious Diseases
M1 - e2020035
ER -
