TY - JOUR
T1 - The use of milrinone in a patient with mitral regurgitation and severe pulmonary hypertension
T2 - A case report
AU - Yamada, Tatsuya
AU - Katori, Nobuyuki
AU - Tagawa, Manabu
AU - Yamamoto, Shinichi
AU - Arisaka, Hiroshi
AU - Takeda, Junzo
PY - 2003/7/1
Y1 - 2003/7/1
N2 - A 65-year-old female with mitral regurgitation was scheduled for the mitral valve surgery. However, because of the severe pulmonary hypertension, the patient needed evaluation on the reversibility of pulmonary hypertension and the safety of the surgical procedure. Milrinone, a phosphodiesterase inhibitor with vasodilating and positive inotropic properties, known to lower pulmonary vascular resistance was administered to the patient. Milrinone showed a prompt decrease of pulmonary artery pressure and an increase of cardiac output, and the cardiac surgery was performed uneventfully. It is considered that milrinone is useful in lowering pulmonary vascular resistance and assessing the reversibility of pulmonary hypertension in patients with severe pulmonary hypertension undergoing cardiac surgery.
AB - A 65-year-old female with mitral regurgitation was scheduled for the mitral valve surgery. However, because of the severe pulmonary hypertension, the patient needed evaluation on the reversibility of pulmonary hypertension and the safety of the surgical procedure. Milrinone, a phosphodiesterase inhibitor with vasodilating and positive inotropic properties, known to lower pulmonary vascular resistance was administered to the patient. Milrinone showed a prompt decrease of pulmonary artery pressure and an increase of cardiac output, and the cardiac surgery was performed uneventfully. It is considered that milrinone is useful in lowering pulmonary vascular resistance and assessing the reversibility of pulmonary hypertension in patients with severe pulmonary hypertension undergoing cardiac surgery.
KW - Milrinone
KW - Mitral regurgitation
KW - Pulmonary hypertension
UR - http://www.scopus.com/inward/record.url?scp=0041311129&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0041311129&partnerID=8YFLogxK
M3 - Article
C2 - 12910980
AN - SCOPUS:0041311129
SN - 0021-4892
VL - 52
SP - 762
EP - 765
JO - Japanese Journal of Anesthesiology
JF - Japanese Journal of Anesthesiology
IS - 7
ER -