Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice

Medicine & Life Sciences

• tranilast 86%
• Graft vs Host Disease 56%
• Homologous Transplantation 16%
• Bone Marrow Transplantation 14%
• Thioredoxins 13%
• Epithelial-Mesenchymal Transition 11%
• Therapeutics 8%
• Fibrosis 7%
• Minor Histocompatibility Antigens 5%
• Lacrimal Apparatus 4%
• Inflammation 4%
• Proteins 3%
• Hematopoietic Stem Cell Transplantation 3%
• Immunoblotting 3%
• Immunosuppressive Agents 2%
• Histology 2%
• B-Lymphocytes 2%
• Transcription Factors 2%
• Oxidative Stress 2%
• Light 2%
• Immunohistochemistry 2%
• Eye 2%
• Pharmaceutical Preparations 1%

Agriculture & Biology

• therapeutics 41%
• mice 30%
• bone marrow transplant 28%
• fibrosis 16%
• thioredoxins 15%
• inflammation 8%
• histocompatibility antigens 6%
• cell transplantation 6%
• lacrimal apparatus 6%
• hematopoietic stem cells 6%
• immunosuppressive agents 5%
• immunoblotting 4%
• immunohistochemistry 4%
• proteins 4%
• histology 4%
• drug therapy 4%
• B-lymphocytes 4%
• animal models 3%
• oxidative stress 3%
• eyes 3%
• transcription factors 3%
• drugs 2%
• methodology 1%

Chemical Compounds

• Tranilast 100%
• Thioredoxin 33%
• Antifibrotic 15%
• Immunosuppressive Agent 11%
• Ocular 11%
• Oxidative Stress 8%
• Antioxidant Agent 6%
• Drug 4%
• Molecule 3%