Three dimensional spheroids formation platform using micro-rotation flow

Hiroki Ota, Koji Deguchi, Ryosuke Yamamoto, Yutaka Kazoe, Koichi Hishida, Yohei Sato, Norihisa Miki

研究成果: Conference contribution

抄録

Hepatocytes increase cell densities and acquire their liver-specific functions during the tissue formation from isolated cells. We developed three dimentional sphedoids formation platform using micro-rotation flow. Based on results of simulations and micro PIV, This chamber were designed to have a circular cylindrical shape with two inlets tangent to the circle at the bottom and two outlet channels at the top. The developed platform could not only form three dimensional spheroids, but also conrol sizes with micro meter scale only by a micro-rotation flow repeatedly. This platform will be applied to be new drug screening systems and hybrid artificial organs.

本文言語English
ホスト出版物のタイトルProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ1183-1185
ページ数3
ISBN(印刷版)9780979806421
出版ステータスPublished - 2009 1月 1
イベント13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
継続期間: 2009 11月 12009 11月 5

出版物シリーズ

名前Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
国/地域Korea, Republic of
CityJeju
Period09/11/109/11/5

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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