@article{4f8a5410c83449f893323b47fcf2c9e2,
title = "Three new malyngamides from the marine cyanobacterium moorea producens",
abstract = "Three new compounds of the malyngamide series, 6,8-di-O-acetylmalyngamide 2 (1), 6-O-acetylmalyngamide 2 (2), and N-demethyl-isomalyngamide I (3), were isolated from the marine cyanobacterium Moorea producens. Their structures were determined by spectroscopic analysis and chemical derivatization and degradation. These compounds stimulated glucose uptake in cultured L6 myotubes. In particular, 6,8-di-O-acetylmalyngamide 2 (1) showed potent activity and activated adenosine monophosphate-activated protein kinase (AMPK).",
keywords = "AMPK, Glucose uptake, Malyngamides, Marine cyanobacteria",
author = "Kosuke Sueyoshi and Aki Yamano and Kaori Ozaki and Shimpei Sumimoto and Arihiro Iwasaki and Kiyotake Suenaga and Toshiaki Teruya",
note = "Funding Information: Acknowledgments: This work was supported in part by a Grant-in-Aid for Young Scientists (B) (21710237) from the Ministry of Education, Culture, Sports, Science and Technology, Japan; University of the Ryukyus Strategic Research Grant. Publisher Copyright: {\textcopyright} 2017 by the authors.",
year = "2017",
month = dec,
doi = "10.3390/md15120367",
language = "English",
volume = "15",
journal = "Marine Drugs",
issn = "1660-3397",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "12",
}
