Two rare cases of invasive thymoma with prominent endobronchial polypoid growth are presented. Chief complaints of both patients, women aged 56 and 62 years, were blood streaked sputum and cough. A large mass shadow located in the mediastinum and lung field was seen on chest x-ray film and an endobronchial polyp was found by bronchoscopy in each patient. Histologic features of the bronchial biopsy specimens were highly suggestive of thymoma. The tumors resected surgically exhibited a unique manner of extension, in which the lumina of bronchi of various sizes were occupied and obliterated by a part of the tumor contiguous to the mediastinum. These tumors were diagnosed histologically as invasive thymoma, predominantly epithelial type, and mixed lymphocytic and epithelial type.
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