TY - JOUR
T1 - Total Synthesis of Biselyngbyaside
AU - Sato, Eisuke
AU - Sato, Miho
AU - Tanabe, Yurika
AU - Nakajima, Naoya
AU - Ohkubo, Akifumi
AU - Suenaga, Kiyotake
N1 - Publisher Copyright:
© 2017 American Chemical Society.
PY - 2017/7/7
Y1 - 2017/7/7
N2 - The first total synthesis of biselyngbyaside, an 18-membered macrolide glycoside, was achieved. The glycoside bond was introduced using the Schmidt method before construction of the 18-membered ring due to the instability of the conjugated diene and the β-hydroxy ester moiety. The macrolactone ring was constructed using the Mitsunobu reaction followed by intramolecular the Stille coupling reaction.
AB - The first total synthesis of biselyngbyaside, an 18-membered macrolide glycoside, was achieved. The glycoside bond was introduced using the Schmidt method before construction of the 18-membered ring due to the instability of the conjugated diene and the β-hydroxy ester moiety. The macrolactone ring was constructed using the Mitsunobu reaction followed by intramolecular the Stille coupling reaction.
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U2 - 10.1021/acs.joc.7b00905
DO - 10.1021/acs.joc.7b00905
M3 - Article
C2 - 28589717
AN - SCOPUS:85022195383
SN - 0022-3263
VL - 82
SP - 6770
EP - 6777
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 13
ER -