@article{61887f0cc5c24bc5820856b783dbcc0e,
title = "Total synthesis of mycestericin A",
abstract = "The first total synthesis of mycestericin A (1) starting from tartrates is described. The Overman rearrangement of an allylic trichloroacetimidate generated a tetra-substituted carbon with nitrogen, and subsequent stereoselective transformations afforded the highly functionalized vinyl iodide. The cross-coupling of the vinyl iodide with a chiral organozinc species under Negishi conditions, followed by deprotection, completed the total synthesis of 1.",
keywords = "Immunosuppressant, Mycestericin A, Negishi coupling, Overman rearrangement, Total synthesis",
author = "Hideyuki Sato and Kazuya Sato and Masatoshi Iida and Hiroyoshi Yamanaka and Takeshi Oishi and Noritaka Chida",
note = "Funding Information: This work was supported in part by Grant-in-Aid for the 21st Century COE Program {\textquoteleft}Keio Life Conjugate Chemistry{\textquoteright} from the Ministry of Education, Culture, Sports, Science, and Technology, Japan. ",
year = "2008",
month = mar,
day = "17",
doi = "10.1016/j.tetlet.2008.01.105",
language = "English",
volume = "49",
pages = "1943--1947",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "12",
}