TY - GEN
T1 - Traction force of smooth muscle cell during growth on a rigid substrate
AU - Jung, U. G.
AU - Tsukagoshi, T.
AU - Takahashi, H.
AU - Kan, T.
AU - Matsumoto, K.
AU - Shimoyama, I.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - This paper reports on the sensor for traction force measurement of a smooth muscle cell during cell growth on a rigid substrate, specially designed for horizontal and vertical directional forces. For quantitative measurement, the cells are cultured only on the sensor pads using a cover chip. The length of the sensor is 1130μm. The size of the sensor pad is 125μm×15μ m×5μm (length×width× thickness). The gaps between the sensor pads are 3μm. We confirmed that the cells spread on the two sensor pads at least. We measured the traction forces of bovine aortic smooth muscle cells (BAOSMCs, CAB35405) using the proposed sensor. When the three cells spread on the pads, the measured traction forces in x and z direction increased 30nN and 20nN for 8 min, respectively.
AB - This paper reports on the sensor for traction force measurement of a smooth muscle cell during cell growth on a rigid substrate, specially designed for horizontal and vertical directional forces. For quantitative measurement, the cells are cultured only on the sensor pads using a cover chip. The length of the sensor is 1130μm. The size of the sensor pad is 125μm×15μ m×5μm (length×width× thickness). The gaps between the sensor pads are 3μm. We confirmed that the cells spread on the two sensor pads at least. We measured the traction forces of bovine aortic smooth muscle cells (BAOSMCs, CAB35405) using the proposed sensor. When the three cells spread on the pads, the measured traction forces in x and z direction increased 30nN and 20nN for 8 min, respectively.
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U2 - 10.1109/MEMSYS.2014.6765633
DO - 10.1109/MEMSYS.2014.6765633
M3 - Conference contribution
AN - SCOPUS:84899028508
SN - 9781479935086
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 290
EP - 293
BT - MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014
Y2 - 26 January 2014 through 30 January 2014
ER -