TY - GEN
T1 - Transplantation of a neurospheroid network onto the rat brain
AU - Kato-Negishi, Midori
AU - Tsuda, Yukiko
AU - Onoe, Hiroaki
AU - Takeuchi, Shoji
PY - 2010/6/1
Y1 - 2010/6/1
N2 - This paper describes a method to transplant neurospheroid network onto the rat brain. We first patterned the uniform sized neurospheroids on the PDMS microchamber, and cultured for 1-2 weeks. After 2-week culture, the neurospheroids tightly connected each other with extending their neuronal processes (e.g. dendrite, axons) and formed neuronal network. We realized that the neurospheroid network can be transferred from the PDMS microchamber onto the glass plate or the rat brain. These transferred neurospheroid network had also neuronal activities. We believe that this transfer method of neurospheroid network should be a useful model for the tissue engineering and medical transplantation.
AB - This paper describes a method to transplant neurospheroid network onto the rat brain. We first patterned the uniform sized neurospheroids on the PDMS microchamber, and cultured for 1-2 weeks. After 2-week culture, the neurospheroids tightly connected each other with extending their neuronal processes (e.g. dendrite, axons) and formed neuronal network. We realized that the neurospheroid network can be transferred from the PDMS microchamber onto the glass plate or the rat brain. These transferred neurospheroid network had also neuronal activities. We believe that this transfer method of neurospheroid network should be a useful model for the tissue engineering and medical transplantation.
UR - http://www.scopus.com/inward/record.url?scp=77952784944&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952784944&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2010.5442386
DO - 10.1109/MEMSYS.2010.5442386
M3 - Conference contribution
AN - SCOPUS:77952784944
SN - 9781424457649
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 1035
EP - 1038
BT - MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest
T2 - 23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010
Y2 - 24 January 2010 through 28 January 2010
ER -