A low dose of miconazole gel (Florid® oral gel) was applied to the basal surface in 10 patients with oral candidiasis and multiple missing teeth wearing denture. Miconazole gel 1 g daily was divided into three portions to be applied only to the basal surface after each meal. Two weeks after the start of application, clinical improvement was observed in 80% of the patients. Candida disappeared in 70% of the patients two weeks after the start of application. An adverse reaction was recognized in one patient. Though the gel was applied only to the basal surface, it was also effective against oral candidiasis extending to the tongue and/or buccal mucosa.
|Oral Therapeutics and Pharmacology
|Published - 2000 1月 1
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