Two Cases of Acute Myeloid Leukemia Evolving into a Chronic Myelomonocytic Leukemia-like State after Induction Therapy

Atsushi Iwama; Akiyoshi Miwa; Toshiyuki Suzuki; Norio Komatsu; Minora Yoshida; Toshio Suda; Shinobu Sakamoto; Yasusada Miura

doi:10.2169/internalmedicine.31.214

Two Cases of Acute Myeloid Leukemia Evolving into a Chronic Myelomonocytic Leukemia-like State after Induction Therapy

Atsushi Iwama, Akiyoshi Miwa, Toshiyuki Suzuki, Norio Komatsu, Minora Yoshida, Toshio Suda, Shinobu Sakamoto, Yasusada Miura

坂口光洋記念講座(発生・分化生物学)

研究成果: Article › 査読

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Two patients with acute myeloid leukemia (AML) developed a chronic myelomonocytic leukemia (CMMoL)-like state after chemotherapy. Both patients showed morphological evidence of myelodysplasia together with acute leukemia at presentation (Case 1: M_5b with trilineage myelodysplasia and Case 2: M₄ with dysmegakaryocytopoiesis). They also showed persistent monocytosis without prominent blast cell proliferation after induction therapy. The possibility was suggested that these two patients were in acute transformation from CMMoL at presentation and returned to a CMMoL-like state after induction therapy.

本文言語	English
ページ（範囲）	214-217
ページ数	4
ジャーナル	Internal Medicine
巻	31
号	2
DOI	https://doi.org/10.2169/internalmedicine.31.214
出版ステータス	Published - 1992 1月 1

ASJC Scopus subject areas

内科学

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10.2169/internalmedicine.31.214

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title = "Two Cases of Acute Myeloid Leukemia Evolving into a Chronic Myelomonocytic Leukemia-like State after Induction Therapy",

abstract = "Two patients with acute myeloid leukemia (AML) developed a chronic myelomonocytic leukemia (CMMoL)-like state after chemotherapy. Both patients showed morphological evidence of myelodysplasia together with acute leukemia at presentation (Case 1: M5b with trilineage myelodysplasia and Case 2: M4 with dysmegakaryocytopoiesis). They also showed persistent monocytosis without prominent blast cell proliferation after induction therapy. The possibility was suggested that these two patients were in acute transformation from CMMoL at presentation and returned to a CMMoL-like state after induction therapy.",

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T1 - Two Cases of Acute Myeloid Leukemia Evolving into a Chronic Myelomonocytic Leukemia-like State after Induction Therapy

AU - Iwama, Atsushi

AU - Miwa, Akiyoshi

AU - Suzuki, Toshiyuki

AU - Komatsu, Norio

AU - Yoshida, Minora

AU - Suda, Toshio

AU - Sakamoto, Shinobu

AU - Miura, Yasusada

PY - 1992/1/1

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N2 - Two patients with acute myeloid leukemia (AML) developed a chronic myelomonocytic leukemia (CMMoL)-like state after chemotherapy. Both patients showed morphological evidence of myelodysplasia together with acute leukemia at presentation (Case 1: M5b with trilineage myelodysplasia and Case 2: M4 with dysmegakaryocytopoiesis). They also showed persistent monocytosis without prominent blast cell proliferation after induction therapy. The possibility was suggested that these two patients were in acute transformation from CMMoL at presentation and returned to a CMMoL-like state after induction therapy.

AB - Two patients with acute myeloid leukemia (AML) developed a chronic myelomonocytic leukemia (CMMoL)-like state after chemotherapy. Both patients showed morphological evidence of myelodysplasia together with acute leukemia at presentation (Case 1: M5b with trilineage myelodysplasia and Case 2: M4 with dysmegakaryocytopoiesis). They also showed persistent monocytosis without prominent blast cell proliferation after induction therapy. The possibility was suggested that these two patients were in acute transformation from CMMoL at presentation and returned to a CMMoL-like state after induction therapy.

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Two Cases of Acute Myeloid Leukemia Evolving into a Chronic Myelomonocytic Leukemia-like State after Induction Therapy

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