Ultrafast 1D MR thermometry using phase or frequency mapping

Chang Sheng Mei, Robert V. Mulkern, Koichi Oshio, Nan Kuei Chen, Bruno Madore, Lawrence P. Panych, Kullervo Hynynen, Nathan J. McDannold

研究成果: Article査読

3 被引用数 (Scopus)


Object To develop an ultrafastMRI-based temperaturemonitoring method for application during rapid ultrasound exposures in moving organs. Materials and methods A slice selective 90? ? 180? pair of RF pulses was used to solicit an echo from a column, which was then sampled with a train of gradient echoes. In a gel phantom, phase changes of each echo were compared to standard gradient-echo thermometry, and temperature monitoring was tested during focused ultrasound sonications. Signal-to-noise ratio (SNR) performance was evaluated in vivo in a rabbit brain, and feasibility was tested in a human heart. Results The correlation between each echo in the acquisition and MRI-based temperature measurements was good (R = 0.98 ± 0.03). A temperature sampling rate of 19Hzwas achieved at 3T in the gel phantom. It was possible to acquire the water frequency in the beating heart muscle with 5-Hz sampling rate during a breath hold. Conclusion Ultrafast thermometry via phase or frequency monitoring along single columns was demonstrated. With a temporal resolution around 50 ms, it may be possible to monitor focal heating produced by short ultrasound pulses.

ジャーナルMagnetic Resonance Materials in Physics, Biology and Medicine
出版ステータスPublished - 2012 2月

ASJC Scopus subject areas

  • 生物理学
  • 放射線技術および超音波技術
  • 放射線学、核医学およびイメージング


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