Update on quinolone-containing rescue therapies for Helicobacter pylori infection

Hideki Mori, Hidekazu Suzuki

研究成果: Review article査読

13 被引用数 (Scopus)

抄録

Third generation of quinolones, such as levofloxacin and moxifloxacin, - containing regimens are often used in second-line or rescue treatment of Helicobacter pylori infection. However, the increasing antibiotic resistance to quinolones affects the efficacies of quinolones-containing therapies in recent years. Therefore, there is a need to enhance the effectiveness of quinolonescontaining therapies. Sitafloxacin, a fourth-generation quinolone, and vonoprazan, a novel potassium-competitive acid blocker, are now available as more effective treatment options. The aim of this paper is to summarize the current evidence of quinolone-containing therapies in rescue treatments, and to discuss the importance of drug sensitivity tests or analysis of gyrA mutation before treatments.

本文言語English
ページ(範囲)1733-1744
ページ数12
ジャーナルWorld Journal of Gastroenterology
26
15
DOI
出版ステータスPublished - 2020 4月 21
外部発表はい

ASJC Scopus subject areas

  • 消化器病学

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