抄録
Background: Choline is a new PET tracer that is useful for the detection of malignant tumor. Choline is a precursor of the biosynthesis of phosphatidylcholine, a major phospholipid in the cell membrane of eukaryotic cells. Malignant tumors have an elevated level of phosphatidylcholine in cell membrane. Thus, choline is a marker of tumor malignancy.Method: The patient was a 51-year-old man with repeated recurrent hemangiopericytoma in the skull base. We performed Choline-PET in this patient after various treatments and compared findings with those of FDG-PET.Results: Choline accumulated in this tumor, but FDG did not accumulate. We diagnosed this tumor as residual hemangiopericytoma and performed the resection of the residual tumor. FDG-PET is not appropriate for skull base tumor detection because uptake in the brain is very strong.Conclusion: We emphasize the usefulness of Choline-PET for the detection of residual hemangiopericytoma in the skull base after various treatments, compared with FDG-PET.
| 本文言語 | English |
|---|---|
| 論文番号 | 3 |
| ジャーナル | Head and Face Medicine |
| 巻 | 8 |
| 号 | 1 |
| DOI | |
| 出版ステータス | Published - 2012 2月 7 |
ASJC Scopus subject areas
- 耳鼻咽喉科学
- 歯科学（全般）
- 臨床神経学